Publications


Du M, Basu A, Fu D, Wu M, Centola M, Jenkins AJ, Hanssen KF, Garg SK, Hammad SM, Scardo JA, Aston CE, and Lyons TJ. Serum inflammatory markers and preeclampsia in type 1 diabetes: a prospective study. Diabetes Care 2013; 36:2054-2961 [Abstract]

 

Hammad SM, Al Gadban MM, Semler AJ, Klein RL. Sphingosine 1-phosphate distribution in human plasma: associations with lipid profiles. J Lipids. 2012;2012:180705 [Abstract]

 

Fu D, Wu M, Zhang J, Du M, Yang S, Hammad SM, Wilson K, Chen J, Lyons TJ. Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy. Diabetologia 2012; 55:3128-40 [Abstract]

 

Yu Y., Hanssen K.F., Kalyanaraman V., Wilson K.W., Chirindel A., Jenkins A.J., Nankervis A.J., Torjesen P., Scholz H., Henriksen T., Lorentzen B., Garg S.K., Menard M.K., Hammad S.M., Scardo J.C., Stanley J.R., Wu M., Basu A., Aston C.E., and Lyons T.J., Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes preeclampsia in Type 1 diabetes. BJOG 2012; 119:1512-1520 [Abstract]

 

Al Gadban M.M., German J., Truman J-P, Soodavar F., Riemer E.C., Twal W.O., Smith K.J., Heller D., Hofbauer A.F., Oates J.C., and Hammad S.M., Lack of nitric oxide synthases increases lipoprotein immune complex deposition in the aorta and elevates plasma sphingolipid levels in lupus. Cellular Immunol. 2012; 276:42-51 [Abstract]

 

Hammad SM, Truman J-P, Al Gadban MM, Smith KJ, Twal WO, and Hamner MB. Altered blood sphingolipidomics and elevated plasma inflammatory cytokines in combat Veterans with post-traumatic stress disorder. Neurobiol Lipids Volume 10, Article 2 (2012) http://neurobiologyoflipids.org/content/10/2/

 

Basu A, Alaupovic P, Wu M, Jenkins AJ, Yu Y, Nankervis AJ, Hanssen KF, Scholz H, Henriksen T, Lorentzen B, Clausen T, Garg SK, Menard MK, Hammad SM, Scardo JC, Stanley JR, Dashti A, Aston CE, and Lyons TJ. Plasma lipoproteins and pre-eclampsia in women with Type 1 diabetes: a prospective study. The Journal of Clinical Endocrinology & Metabolism 2012; 97:1752-1762. [Abstract]

 

El-Shewy H.M., Sohn M., Wilson P., Hammad S.M., Luttrell L.M., and Jaffa A.A., Low-density lipoprotein induced expression of connective tissue growth factor via transactivation of sphingosine 1-phosphate receptors in mesangial cells. Molecular Endocrinology 2012; 26:833-845. [Abstract]

 

Truman J-P, Al Gadban M.M., Smith K.J., Jenkins R.W., Mayroo N., Virella G., Lopes-Virella M.F., Bielawska A., Hannun Y.A., and Hammad S.M. Differential regulation of acid sphingomyelinase in monocytes stimulated with oxidized LDL and oxidized LDL immune complexes: role in phagocytosis and cytokine release. Immunology 2012; 136:30-45. [Abstract]

 

Hammad SM. Blood sphingolipids in homeostasis and pathobiology. Adv Exp Med Biol. 2011 721:57-66. [Abstract]

 

Azar M, Basu A, Jenkins AJ, Nankervis AJ, Hanssen KF, Scholz H, Henriksen T, Garg SK, Hammad SM, Scardo JA, Aston CE, Lyons TJ. Serum carotenoids and fat-soluble vitamins in women with type 1 diabetes and preeclampsia: a longitudinal study. Diabetes Care. 2011 Jun;34(6):1258-64. [Abstract]

 

Truman JP, Al Gadban MM, Smith KJ, Hammad SM. Acid sphingomyelinase in macrophage biology. Cell Mol Life Sci. 2011 Oct;68(20):3293-305. Cover page [Abstract]

 

Pilcher ES, Mauldin M, Hammad SM, McDougall C, Howell D. Interprofessional Faculty Development Institute: Empowering Leaders in Advanced Teambuilding. Journal of Dental Education. 2011 75(2):190-256.

 

Hammad S.M. Blood sphingolipids in homeostasis and pathobiology. In: Cowart A, ed. Sphingolipids and Metabolic Disease. Austin/New York: Landes Bioscience/Springer, 2011.

 

Al Gadban M.M., Smith K.J., Soodavar F., Piansay C., Chassereau C., Twal W.O., Klein R.L., Virella G., Lopes-Virella M.F., and Hammad S.M. Differential Trafficking of Oxidized LDL and Oxidized LDL Immune Complexes in Macrophages: Impact on Oxidative Stress. PLoS ONE 5 (2010): e12534. [Abstract]

 

Hammad SM, Pierce JS, Soodavar F, Smith KJ, Al Gadban MM, Rembiesa B, Klein RL, Hannun YA, Bielawski J, Bielawska A. Blood sphingolipidomics in healthy humans: Impact of sample collection methodology. J Lipid Res. 2010; 51:3074-87. [Abstract]

 

Lee MH*, Hammad SM*, Semler AJ, Luttrell LM, Lopes-Virella MF, Klein RL. HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate. J Lipid Res. 2010; 51:2619-28. [Abstract]

 

Smith KJ, Twal WO, Soodavar F, Virella G, Lopes-Virella MF, and Hammad, SM, HSP70B’ expression and release in response to human oxidized LDL immune complex in human monocytic cells. J Biol Chem. 2010;21;285(21):15985-93 [Abstract]


Diffley JM, Wu M, Sohn M, Song W, Hammad SM, Lyons TJ. Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways. Mol Vis. 2009;15:135-45 [Abstract]

Yu Y, Jenkins AJ, Nankervis AJ, Hanssen KF, Scholz H, Henriksen T, Lorentzen B, Clausen T, Garg SK, Menard MK, Hammad SM, Scardo JC, Stanley JR, Dashti A, May K, Lu K, Aston CE, Wang JJ, Zhang SX, Ma JX, Lyons TJ. Anti-angiogenic factors and pre-eclampsia in type 1 diabetic women. Diabetologia. 2009 Jan;52(1):160-8 [Abstract]

 

Argraves KM, Gazzolo PJ, Groh EM, Wilkerson BA, Matsuura BS, Twal WO, Hammad SM, Argraves WS. High density lipoprotein-associated sphingosine 1-phosphate promotes endothelial barrier function. J Biol Chem. 2008 Sep 5;283(36):25074-81[Abstract]

Hammad SM, Twal WO, Barth JL, Smith KJ, Saad AF, Virella G, Argraves WS, Lopes-Virella MF. Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells. Atherosclerosis. 2009 Feb;202(2):394-404 [Abstract]

Twiner MJ, Ryan JC, Morey JS, Smith KJ, Hammad SM, Van Dolah FM, Hess P, McMahon T, Satake M, Yasumoto T, Doucette GJ. Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid. Genomics. 2008 Mar;91(3):289-300 [Abstract]

Hammad SM, Crellin HG, Wu BX, Melton J, Anelli V, Obeid LM. Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages. Prostaglandins Other Lipid Mediat. 2008 Mar;85(3-4):107-14 [Abstract]

Hammad S.M., Taha T.A., Nareika A., Johnson K.R., Lopes-Virella M.F., and Obeid L.M. Oxidized LDL immune complexes induce release of sphingosine kinase in human U937 monocytic cells. Prostaglandins Other Lipid Mediat., 79:126-140, 2006. [Abstract]

Hammad S.M., Hazen-Martin D.J., Sohn M., Eldridge L., Powell-Braxton L., Won W., and Lyons T.J. Nephropathy in a Hypercholesterolemic Mouse Model with Streptozotocin-Induced Diabetes. Kidney and Blood Pressure Research, 26:351-361, 2003. [Abstract]

Hammad S.M., Powell-Braxton L., Otvos J.D., Eldridge L., Won W., and Lyons T.J. Lipoprotein Subclass Profiles of Hyperlipidemic Diabetic Mice Measured by Nuclear Magnetic Resonance Spectroscopy. Metabolism, 52:916-921, 2003. [Abstract]

Hammad S.M., Barth J.L., Knaak C., and Argraves W.S. Megalin acts in concert with cubilin to mediate endocytosis of HDL. J. Biol. Chem., 275:12003-12008, 2000. [Abstract] pdf

Hammad S.M., Stefansson S., Twal W.O., Drake C.J., Fleming P., Remaley A., Brewer H.B., and Agraves W.S. Cubilin, the endocytic receptor for intrinsic factor-vitamin B12 complex, mediates high density lipoprotein holoparticle endocytosis. Proc Natl. Acad. Sci. USA, 96:10158-10163, 1999. [Abstract] pdf

Hammad S.M., Siegel H.S., and Marks H.L.. Total cholesterol, total triglycerides, and cholesterol distribution among lipoproteins as predictors of atherosclerosis in selected lines of Japanese quail. Comp. Biochem. Physiol. A, 119A:485-492, 1997. [Abstract]

Hammad S.M., Ranganathan S., Loukinova E., Twal W.O., and Argraves W.S. Interaction of apolipoprotein J-amyloid β-peptide complex with low density lipoprotein receptor-related protein-2/megalin: a mechanism to prevent pathalogical accumulation of amyloid β-peptide. J. Biol. Chem., 272:18644-18649, 1997. [Abstract] pdf

Hammad S.M., Siegel H.S., and Marks H.L. Dietary cholesterol metabolism in Japanese quail lines selected for plasma cholesterol levels. Proc. Soc. Exp. Biol. Med. 214:62-68, 1997. [Abstract]

Hammad S.M., Siegel H.S., and Marks H.L. Dietary cholesterol effects on plasma and yolk cholesterol fractions in selected lines of Japanese quail. Poultry Sci. 75:933-942, 1996. [Abstract]

Siegel H.S., Hammad S.M., and Marks H.L. Atherosclerosis in Japanese quail males selected for high or low plasma cholesterol. Poultry Sci. 74:1712-1716, 1995. [Abstract]

Siegel H.S., Hammad S.M., Leach R.M., Barbato G.F., Green M.H., and Marks H.L. Dietary cholesterol and fat saturation effects on plasma esterified and unesterified cholesterol in selected lines of Japanese quail females. Poultry Sci. 74:1370-1380, 1995. [Abstract]

Hammad S.M., Siegel H.S., Marks H.L., and Barbato G.F. A fast HPLC analysis of cholesterol and cholesteryl esters in avian plasma. J. Liquid Chromatogr. 15:2005-2014, 1992