Current research publications

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Liu Y, Conlon DM, Bi X, Slovik KJ, Shi J, Edelstein HI, Millar JS, Javaheri A, Cuchel M, Pashos EE, Iqbal J, Hussain MM, Hegele RA, Yang W, Duncan SA, Rader DJ, Morrisey EE. Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress. Cell Rep. 2017, 19(7):1456-1466. PMID: 28514664 doi:10.1016/j.celrep.2017.04.064

Iqbal J, Walsh MT, Hammad SM, Hussain MM. Sphingolipids and Lipoproteins in Health and Metabolic Disorders. Trends Endocrinol Metab. 2017, Apr 24 pii: S1043-2760(17)30041-3 PMID: 28462811 doi:10.1016/j.tem.2017.03.005

Kourtidis A, Lu R, Pence L, Anastasiadis PZ. A central role for cadherin signaling in cancer. Exp Cell Res. 2017, Apr 12 PMID: 28412244 doi:10.1016/j.yexcr.2017.04.006

Ghatak S, Markwald RR, Hascall VC, Dowling W, Lottes RG, Baatz JE, Beeson G, Beeson CC, Perrella MA, Thannickal VJ, Misra S. TGF beta-1 regulates CD44v6 expression and activity through ERK-induced EGR1 in pulmonary fibrogenic fibroblasts. J Biol Chem. 2017, Apr 7. pii: jbc.M116.752451. PMID: 28389562 doi:10.1074/jbc.M116.752451

Ghatak S, Hascall VC, Markwald RR, Feghali-Bostwick C, Artlett CM, Gooz M, Bogatkevich GS, Atanelishvili I, Silver RM, Wood J, Thannickal VJ, Misra S. TGF beta-1 induced CD44v6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis. J Biol Chem. 2017, Apr 7. pii: jbc.M116.752469. PMID: 28389561 doi:10.1074/jbc.M116.752469

Pashos EE, Park Y, Wang X, Raghavan A, Yang W, Abbey D, Peters DT, Arbelaez J, Hernandez M, Kuperwasser N, Li W, Lian Z, Liu Y, Lv W, Lytle-Gabbin SL, Marchadier DH, Rogov P, Shi J, Slovik KJ, Stylianou IM, Wang L, Yan R, Zhang X, Kathiresan S, Duncan SA, Mikkelsen TS, Morrisey EE, Rader DJ, Brown CD, Musunuru K. Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci. Cell Stem Cell. 2017, Apr 6;20(4):558-570.e10 PMID: 28388432 doi:10.1016/j.stem.2017.03.017

Cayo MA, Mallanna SK, Di Furio F, Jing R, Tolliver LB, Bures M, Urick A, Noto FK, Pashos EE, Greseth MD, Czarnecki M, Traktman P, Yang W, Morrisey EE, Grompe M, Rader DJ, Duncan, SA. A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia Cell Stem Cell. 2017, 20(4), 6 April 2017, Pages 478-489.e5 PMID: 28388428 PMCID: PMC5385853 doi:10.1016/j.stem.2017.01.011

Jing R, Duncan CB, Duncan SA. A small molecule screen reveals that HSP90β promotes the conversion of iPSC-derived endoderm to a hepatic fate and regulates HNF4A turnover Development. 2017, Mar 30 PMID: 28360131 doi:10.1242/dev.146845

Bi X, Pashos EE, Cuchel M, Lyssenko NN, Hernandez M, Picataggi A, McParland J, Yang W, Liu Y, Yan R, Yu C, DerOhannessian SL, Phillips MC, Morrisey EE, Duncan SA, Rader DJ. ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion. EBioMedicine. 2017, Mar 14. pii: S2352-3964(17)30105-6 PMID: 28330813 doi:10.1016/j.ebiom.2017.03.018

Lisy M, Kalender G, Schenke-Layland K, Brockbank KG, Biermann A, Stock UA. Allograft Heart Valves: Current Aspects and Future Applications. Biopreserv Biobank. 2017, Feb 2 PMID: 28151005 doi:10.1089/bio.2016.0070


Last updated on 17-Apr-2017
 
 

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